PM dmdicks or JonGTR. Both have run unopened Beta blocks while boosting.
Thing is though, trying to find someone who has daily driven a 300HPish Beta-powered car for a significant (2 years+) amount of time may be tricky - and to answer your question, our internals are not forged, but the block is iron.
I have 100% confidence (whatever that's worth to you) that with good tuning (meaning that your AFRs are kept under control) and turbo choice, 300HP should be no issue to an unopened Beta engine as far as reliability is concerned.
If I were to do it, I would upgrade my pistons just for peace of mind, and room to play in the future, because as all boosted guys/gals know...PSI is more addictive than crack, and you WILL want more.
-BRR